head and neck cancer
Conditions
Interventions
A:Protection of parotid gland and oral cavity
B:Protection of Submandibular gland and oral cavity
C:Protect oral cavity only
D:Protect both parotid gland, submandibular gland, and oral cavity
Sponsors
The General Hospital of People’s Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. the primary tumor is head and neck malignant tumor, including the parts of the mouth, throat, nasal cavity, sinuses, salivary gland; 2. the imaging examination ( MRI ) was enhanced, and the CT enhancement was used in Mr examination. The neck superficial linbajiecai ( super ) confirmed the scope and lymph node metastasis of primary disease; 3. definite pathological diagnosis and clinical stage; 4. life expectancy is more than 2 years; 5. cervical and supraclavicular lymph node metastasis is allowed; 6. no organ transfer; 7. allow induction chemotherapy, synchronous chemotherapy, consolidation of chemotherapy, targeted drug therapy and other treatment modalities; 8. no operation intervention was carried out; 9. the functional state score ( KPS ) score = 70, the physical status score ( ECOG ): 0-1socre; 10. Aged 18-65 years old; 11. complete medical records ( history, physical examination, related examination, treatment); 12. the feasible saliva flow rate and the table score of the regular dry mouth; 13. voluntary participation and written and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. other rheumatic immune system diseases such as Sjogren's syndrome; 2. salivary gland cyst operation or other physical therapy; 3. history of head and neck surgery trauma; 4. head and neckradiationthearpy; 5. refusal or unable to sign the written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Velocity of saliva;xerostomia score;xerostomia score;OS;DFS; | — |
Countries
China
Contacts
Public ContactMa Lin
The General Hospital of People’s Liberation Army
Outcome results
None listed