Cervical Carcinom
Conditions
Interventions
fuor:Biomaker
Sponsors
Guizhou Province Cancer Hospital Affiliated to Guizhou Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients with histologically cervical biopsy confirmed cervical cancer before treatment and has been in immunohistochemistry, which items to include HIF-1 alpha, CD44v6, COX-2, EGFR; 2. After more than two obstetrics and gynecology gynecological examinations and definiting diagnosis and FIGO stage, and there is a measurable tumor lesions; 3. Before entering the experiment, patients were not treated with radiotherapy, chemotherapy and surgery; 4. Karnofsky score =70 points; 5. Women aged 18 to 70 years; 6. Normal bone marrow function (WBC> 4.0×10^9/L, PLT=100×10^9/L, Hbt>70g/L); 7. Liver function: alanine aminotransferase (ALT), aspartate aminotransferase (AST) <upper limit of normal (ULN) of 1.5 times; total bilirubin <1.5×ULN; renal function: serum creatinine <1.5×ULN; 8. There is no major organ dysfunction, no serious complications, such as hypertension, diabetes, coronary heart disease and a history of mental illness; 9. This study could be understood and the informed consent could be signed.
Exclusion criteria
Exclusion criteria: 1. patients were treated with radiotherapy, chemotherapy and surgery.; 2. Karnofsky score <70 points; 3. Severe lung or heart disease history, activity of systemic infection, drug abuse or alcohol addiction; 4. Creatinine clearance <30ml / min; 5. After entering the experiment, patients receive chronic systemic immunotherapy or hormone therapy; 6. Pregnancy (via the urine or serum ß-HCG test confirmed) or during lactation; 7. Researchers comfirm that patient has a physical or mental illness, which causes the patient was unable to fully understand the possible complications in this study. And patient with or without civil capacity or with limited capacity for civil conduct.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| short-term curative effect; | — |
Countries
China
Contacts
Public ContactJiehui Li
Guizhou Medical University
Outcome results
None listed