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The role of eosinophils in remodeling process of chronic rhinosinusitis with nasal polyps

clinical research of remodeling process of chronic rhinosinusitis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-17014207
Enrollment
Unknown
Registered
2017-12-28
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic rhinosinusitis

Interventions

chronic rhinosinusitis with nasal polyps:corticosteroid therapy
normal control group: no intervention
chronic rhinosinusitis without nasal polyps:corticosteroid therapy

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) normal control group: patients without sinusitis; (2) chronic sinusitis without nasal polyps (CRSsNP); (3) chronic sinusitis with nasal polyps. All of the patients did not have corticosteroid therapy topical or systematic in recent 1 month.

Exclusion criteria

Exclusion criteria: patients with history of endoscopic sinus surgery; patients with choanal polyp; patients with fungal sinusitis. patients with cystic fibrosis, patients with cilia dysfunction syndrome and patients with acute sinusitis.

Design outcomes

Primary

MeasureTime frame
E-calnexin;Vimentin;Eosinophils;—

Countries

China

Contacts

Public ContactMingjie Wang

Beijing Tongren Hospital, Capital Medical University

mingjiewang@139.com+86 13681319848

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026