sternal tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years old male and female; 2. In line with the diagnosis: a huge chest wall tumor, according to the clinical data to consider the expansion of the tumor resection, the need for thoracic reconstruction; 3. According to ECOG score standard Note 1, physical status level 0-2 level; 4. liver and kidney function indicators: serum bilirubin less than twice the upper limit of normal range, alanine aminotransferase (ALT, Glutamic-OxalateTransaminase) or less than three times the upper limit of normal, serum creatinine less than two Times the normal range of the upper limit. The above exception, if considered as a result of tumor invasion, can be excluded; 5. Left ventricular ejection function (LVEF, Left Ventricular Eject Function) up to 45% or greater than 45%; 6. Can accept artificial bone material implantation surgery; 7. Sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. There is a systemic tumor metastasis; 2. tumor invasion of violations of the chest wall outside the site; 3. Tumor infringement of intrathoracic organs, it is difficult to complete excision; 4. Infectious Hepatitis B Virus, Hepatitis C Virus and Human Immunodeficiency Virus; 5. Uncontrolled active infections: systemic fungal, bacterial, viral or other infections; 6. History of Central Nervous System Diseases 7. Patients with uncontrolled mental illness; 8. Incorporate other life-threatening severe organ failure; 9. Major surgery for non-diagnostic purposes within four weeks; 10. Have received other clinical studies within four weeks (observational studies are not included); 11. Pregnant or lactating women; 12. Other things that researchers think are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lung function; | — |
Countries
China
Contacts
The Second Xiangya Hospital, Central South University