Facial paralysis
Conditions
Interventions
Masseter to facial nerve repair:Masseter to facial nerve repair
Dual innervation:Dual innervation by masseter and cross facial nerve
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Unilateral complete facial palsy patients; 2. Proximal nerve defect, which renders directed nerve repair impossible. Eg. Temporal bone fracture or facial palsy caused by otology surgery or intracranial surgery; 3. Dennervation time should be less than 3 years and fibrillation potential should be detected. Nerve repairs should be considered for cases of nerve transection. Nerve repair will be suggested for cases with no sign of clinical recovery or EMG signal. For cases with no clinical recovery after 7 month, but EMG suggested multiple orential potential, an additional two-month observation will be suggested. If no future improvement were observed clinically or in the EMG signals, nerve repair will be suggested; 4. Patients aged between 18 and 65 years old; 5. Patients who are willing to join the study and sign the consent form.;Inclusion criteria: 1. Unilateral complete facial palsy patients; 2. Proximal nerve defect, which renders directed nerve repair impossible. Eg. Temporal bone fracture or facial palsy caused by otology surgery or intracranial surgery; 3. Dennervation time should be less than 3 years and fibrillation potential should be detected. Nerve repairs should be considered for cases of nerve transection. Nerve repair will be suggested for cases with no sign of clinical recovery or EMG signal. For cases with no clinical recovery after 7 month, but EMG suggested multiple orential potential, an additional two-month observation will be suggested. If no future improvement were observed clinically or in the EMG signals, nerve repair will be suggested; 4. Patients aged between 18 and 65 years old; 5. Patients who are willing to join the study and sign the consent form.;Inclusion criteria: 1. Unilateral complete facial palsy patients; 2. Proximal nerve defect, which renders directed nerve repair impossible. Eg. Temporal bone fracture or facial palsy caused by otology surgery or intracranial surgery; 3. Dennervation time should be less than 3 years and fibrillation potential should be detected. Nerve repairs should be considered for cases of nerve transection. Nerve repair will be suggested for cases with no sign of clinical recovery or EMG signal. For cases with no clinical recovery after 7 month, but EMG suggested multiple orential potential, an additional two-month observation will be suggested. If no future improvement were observed clinically or in the EMG signals, nerve repair will be suggested; 4. Patients aged between 18 and 65 years old; 5. Patients who are willing to join the study and sign the consent form.;Inclusion criteria: 1. Unilateral complete facial palsy patients; 2. Proximal nerve defect, which renders directed nerve repair impossible. Eg. Temporal bone fracture or facial palsy caused by otology surgery or intracranial surgery; 3. Dennervation time should be less than 3 years and fibrillation potential should be detected. Nerve repairs should be considered for cases of nerve transection. Nerve repair will be suggested for cases with no sign of clinical recovery or EMG signal. For cases with no clinical recovery after 7 month, but EMG suggested multiple orential potential, an additional two-month observation will be suggested. If no future improvement were observed clinically or in the EMG signals, nerve repair will be suggested; 4. Patients aged between 18 and 65 years old; 5. Patients who are willing to join the study and sign the consent form.;Inclusion criteria: 1. Unilateral complete facial palsy patients; 2. Proximal nerve defect, which renders directed nerve repair impossible. Eg. Temporal bone fracture or facial palsy caused by otology surgery or intracranial surgery; 3. Dennervation time should be less than 3 years and fibrillation potential should be detected. Nerve repairs should be considered for cases of nerve transection. Nerve repair will be suggested for cases with no sign of clinical recovery or EMG signal. For cases with no clinical recovery after 7 month, but EMG suggested multiple orential potential, an additional two-month observation will be suggested. If no future improvement were observed clinically or in the EMG signals, nerve repair will be suggested; 4. Patients aged between 18 and 65 years old; 5. Patients who are willing to join the study and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who had more than one procedures of facial reanimation surgeries; 2. Patients with masseter nerve malfunction of either side; 3. Patients with severe heart, liver or kidney malfunction(Hart function level3 or 4, ALT higher than 1.5 fold of normal value, Cr>133umol/L); Patients with hemopoietic dysfunction, inclination of hemorrhage; Patients with systemic diseases, eg. Leukemia, severe diabetes, hypertension, any kind of cardiac diseases; Patient in pregnancy or breast feeding; 4. clinical exams suggest tumor, development or treatment of which will compromise the result of nerve repair; 5. Patients with psychiatric or neurological disorders or malignant tumor; 6. Patients with bad compliance or short life span and can not complete the treatment; 7. Patients who can not understand the procedure or has unrealistic expectations; 8. Drug users.;Exclusion criteria: 1. Patients who had more than one procedures of facial reanimation surgeries; 2. Patients with masseter nerve malfunction of either side; 3. Patients with severe heart, liver or kidney malfunction(Hart function level3 or 4, ALT higher than 1.5 fold of normal value, Cr>133umol/L); Patients with hemopoietic dysfunction, inclination of hemorrhage; Patients with systemic diseases, eg. Leukemia, severe diabetes, hypertension, any kind of cardiac diseases; Patient in pregnancy or breast feeding; 4. clinical exams suggest tumor, development or treatment of which will compromise the result of nerve repair; 5. Patients with psychiatric or neurological disorders or malignant tumor; 6. Patients with bad compliance or short life span and can not complete the treatment; 7. Patients who can not understand the procedure or has unrealistic expectations; 8. Drug users.;Exclusion criteria: 1. Patients who had more than one procedures of facial reanimation surgeries; 2. Patients with masseter nerve malfunction of either side; 3. Patients with severe heart, liver or kidney malfunction(Hart function level3 or 4, ALT higher than 1.5 fold of normal value, Cr>133umol/L); Patients with hemopoietic dysfunction, inclination of hemorrhage; Patients with systemic diseases, eg. Leukemia, severe diabetes, hypertension, any kind of cardiac diseases; Patient in pregnancy or breast feeding; 4. clinical exams suggest tumor, development or treatment of which will compromise the result of nerve repair; 5. Patients with psychiatric or neurological disorders or malignant tumor; 6. Patients with bad compliance or short life span and can not complete the treatment; 7. Patients who can not understand the procedure or has unrealistic expectations; 8. Drug users.;Exclusion criteria: 1. Patients who had more than one procedures of facial reanimation surgeries; 2. Patients with masseter nerve malfunction of either side; 3. Patients with severe heart, liver or kidney malfunction(Hart function level3 or 4, ALT higher than 1.5 fold of normal value, Cr>133umol/L); Patients with hemopoietic dysfunction, inclination of hemorrhage; Patients with systemic diseases, eg. Leukemia, severe diabetes, hypertension, any kind of cardiac diseases; Patient in pregnancy or breast feeding; 4. clinical exams suggest tumor, development or treatment of which will compromise the result of nerve repair; 5. Patients with psychiatric or neurological disorders or malignant tumor; 6. Patients with bad compliance or short life span and can not complete the treatment; 7. Patients who can not understand the procedure or has unrealistic expectations; 8. Drug users.;Exclusion criteria: 1. Patients who had more than one procedures of facial reanimation surgeries; 2. Patients with masseter nerve malfunction of either side; 3. Patients with severe heart, liver or kidney malfunction(Hart function level3 or 4, ALT higher than 1.5 fold of normal value, Cr>133umol/L); Patients with hemopoietic dysfunction, inclination of hemorrhage; Patients with systemic diseases, eg. Leukemia, severe diabetes, hypertension, any kind of cardiac diseases; Patient in pregnancy or breast feeding; 4. clinical exams suggest tumor, development or treatment of which will compromise the result of nerve repair; 5. Patients with psychiatric or neurological disorders or malignant tumor; 6. Patients with bad compliance or short life span and can not complete the treatment; 7. Patients who can not understand the procedure or has unrealistic expectations; 8. Drug users.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Terzis Scale;oral commissure excursion;resting score;Mehta Score;EMG;fMRI;live video analysis; | — |
Countries
China
Contacts
Public ContactWei Wang;Wei Wang;Wei Wang;Wei Wang;Wei Wang ;;;;
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Outcome results
None listed