Obstructive Sleep Apnea (OSA)
Conditions
Interventions
CPAP Group:CPAP (Contious Positive Airway Pressure)
Sponsors
Beijing Tsinghua Changgung Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) untreated patients diagnosed with OSA; (2) agef between 18 and 75 years; (3) full night PSG showed both REM (rapid eye movement) stage and NREM (non-rapid eye movement) stage, and contained both supine position and lateral position, and the total supine-sleep time > 30min; (4) sleep efficiency = 75%. ;Inclusion criteria: (1) untreated patients diagnosed with OSA; (2) agef between 18 and 75 years; (3) full night PSG showed both REM (rapid eye movement) stage and NREM (non-rapid eye movement) stage, and contained both supine position and lateral position, and the total supine-sleep time > 30min; (4) sleep efficiency = 75%. ;Inclusion criteria: (1) untreated patients diagnosed with OSA; (2) agef between 18 and 75 years; (3) full night PSG showed both REM (rapid eye movement) stage and NREM (non-rapid eye movement) stage, and contained both supine position and lateral position, and the total supine-sleep time > 30min; (4) sleep efficiency = 75%. ;Inclusion criteria: (1) untreated patients diagnosed with OSA; (2) agef between 18 and 75 years; (3) full night PSG showed both REM (rapid eye movement) stage and NREM (non-rapid eye movement) stage, and contained both supine position and lateral position, and the total supine-sleep time > 30min; (4) sleep efficiency = 75%. ;Inclusion criteria: (1) untreated patients diagnosed with OSA; (2) agef between 18 and 75 years; (3) full night PSG showed both REM (rapid eye movement) stage and NREM (non-rapid eye movement) stage, and contained both supine position and lateral position, and the total supine-sleep time > 30min; (4) sleep efficiency = 75%.
Exclusion criteria
Exclusion criteria: hypothyroidism, vocal cord paralysis, acromegalis and any other disease causing secondary OSA, conscious disturbance, active psychiatric disease, central apnea, severe restrictive or obstructive pulmonary disease, neuromuscular disease, and significant craniofacial anomalies affecting airway.;Exclusion criteria: hypothyroidism, vocal cord paralysis, acromegalis and any other disease causing secondary OSA, conscious disturbance, active psychiatric disease, central apnea, severe restrictive or obstructive pulmonary disease, neuromuscular disease, and significant craniofacial anomalies affecting airway.;Exclusion criteria: hypothyroidism, vocal cord paralysis, acromegalis and any other disease causing secondary OSA, conscious disturbance, active psychiatric disease, central apnea, severe restrictive or obstructive pulmonary disease, neuromuscular disease, and significant craniofacial anomalies affecting airway.;Exclusion criteria: hypothyroidism, vocal cord paralysis, acromegalis and any other disease causing secondary OSA, conscious disturbance, active psychiatric disease, central apnea, severe restrictive or obstructive pulmonary disease, neuromuscular disease, and significant craniofacial anomalies affecting airway.;Exclusion criteria: hypothyroidism, vocal cord paralysis, acromegalis and any other disease causing secondary OSA, conscious disturbance, active psychiatric disease, central apnea, severe restrictive or obstructive pulmonary disease, neuromuscular disease, and significant craniofacial anomalies affecting airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AHI (Apnea Hypopnea Index);lowest oxygen saturation;mean oxygen saturation;CT90;minimum velopharyngeal cross-sectional area;minimum velopharyngeal transverse diameter;minimum velopharyngeal anteroposterior diameter;minimum glossopharyngeal cross-sectional area;minimum glossopharyngeal transverse area;minimum glossopharyngeal anteroposterior diameter;mandibule-hyroid distance;genitoglossal myoelectricity;C-reactive protein (CRP);FBG (fasting blood glucose);fasting insulin level;blood lipid level;Blood Pressure;Blood Pressure;serum uric acid (UA);survival time, mortality, disability rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| ESS (Epworth Sleepiness Scale);The Quality of Life Scale (QOLS); | — |
Countries
China
Contacts
Public ContactJingying Ye;Jingying Ye;Jingying Ye;Jingying Ye;Jingying Ye ;;;;
Beijing Tsinghua Changgung Hospital;Beijing Tsinghua Changgung Hospital;Beijing Tsinghua Changgung Hospital;Beijing Tsinghua Changgung Hospital;Beijing Tsinghua Changgung Hospital
Outcome results
None listed