decompensated liver cirrhosis
Conditions
Interventions
intraportal autologous bone marrow transfusion:intraportal autologous bone marrow transfusion
Sponsors
Shanghai Public Health Clinical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients attended the Shanghai Public Health Clinical Center, China, were diagnosed with decompensated liver cirrhosis caused by chronic hepatitis B, hepatitis C, or alcoholic cirrhosis and autoimmune liver cirrhosis. Patients required splenectomy because of portal hypertension or hypersplenism and met all the following inclusion criteria: aged 20–70 years, decompensated liver cirrhosis, abnormal serum albumin (ALB) and/or bilirubin and/or prothrombin time, and no viable hepatocellular carcinoma seen on a computed tomography (CT) scan.
Exclusion criteria
Exclusion criteria: The exclusion criteria were evidence of extrahepatic biliary diseases, severe cardiac insufficiency, and no severe diseases such as stroke or myocardial infarction in the last 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| alanine aminotransferase;serum albumin;total bilirubin;prothrombin activity;Cholinesterase;liver stiffness measurement; | — |
Secondary
| Measure | Time frame |
|---|---|
| a-fetoprotein; | — |
Contacts
Public ContactBaochi Liu
Shanghai Public Health Clinical Center
Outcome results
None listed