adenomyosis
Conditions
Interventions
A group:HIFU+LNG-IUS
B group:GnRH-a+LNG-IUS
C group:HIFU+GnRH-a+LNG-IUS
Sponsors
Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Female
Age
25 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Premenopausal women aged between 25 to 50 years; (2) Confirmed adenomyosis by history, examination,CA125, MRI or ultrasound; (3) Maxium diameter of Uterine is less than or equal to 7cm, maxium diameter of adenomyoma is less than or equal to 6cm; (4) Receive no other steroid hormone medications within 3 months; (5) Be voluntory to this trial and sign the consent form.
Exclusion criteria
Exclusion criteria: (1) Maxium diameter of Uterine is more than 7cm, maxium diameter of adenomyoma is more than or equal to 6cm; (2) Be allergic to or contraindicated to HIFU, GnRH-a, or LNG-IUS; (3) Be pregnant, with accute genital tract inflamation or gynecological malignant diseases such as ovarian cancer; (4) Receive other steroid hormone medications within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| dysmenorrhea symptoms;Dysmenorrhea degree;Lesion reduction rate;Menstrual volume;Uterine volume reduction rate;The rate of LNG-IUS abscission;The rate of downward movement of LNG-IUS;Ablation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| HGB;CA125;Recurrence rate; | — |
Contacts
Public ContactZhang Yu
Xiangya Hospital of Central South University
Outcome results
None listed