chronic kidney disease
Conditions
Interventions
LFHD group:Low-Flux hemodialysis
HFHD group:High-Flux hemodialysis
HDF group:Hemodiafiltration
HD+HPgroup:Hemodialysis combined with hemoperfusion
Sponsors
Air Force General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) maintenance hemodialysis >3 months, Kt/V>1.2; (2) regular dialysis, 3 times/week, 4 hours/time; (3) HP treatment was not accepted before the study; (4) no residual renal function (<500ml/d); (5) voluntary subjects and sign the consent form.
Exclusion criteria
Exclusion criteria: (1) known to dialysis hemoperfusion materials, allergic reactions, is contraindicated or not tolerated; (2) platelet count < 60*10^9/L; (3) serum albumin <30g/l; (4) patients with coagulation disorders, severe bleeding tendency or active bleeding; (5) patients with acute infection in the near future; (6) severe heart, lung and nervous system diseases and other severe cases; (7) non self arteriovenous fistula hemodialysis access
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hippuric acid;p-cresyl sulfate;indoxyl sulfate;3-carboxy-4-methyl-5-propyl-2-furanpropionic acid;ß2-Microglobulin;Dialysis adequacy(Kt/V);Serum calcium,;Serum phosphorus;parathyroid hormone;Serum albumin;Ferritin;Transferrin saturation;Blood pressure;Quality of life; | — |
Countries
China
Contacts
Public ContactLun Lide
Air Force General Hospital
Outcome results
None listed