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Actinidia Chinensis Planch improves the indices of antioxidant and anti-inflammation status of Type 2 diabetes mellitus by activating Keap1 and Nrf2 via the upregulation of microRNA-424

Actinidia Chinensis Planch improves the indices of antioxidant and anti-inflammation status of Type 2 diabetes mellitus by activating Keap1 and Nrf2 via the upregulation of microRNA-424

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-17011087
Enrollment
Unknown
Registered
2017-04-07
Start date
2015-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

PG and CG:kiwi fruit

Sponsors

The First Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) the patients seldom consumed fruits daily; 2) had normal work and spouse; 3) they wanted to join our research, such as receiving FJACP treatment; 4) the patients were diagnosed with T2DM; 5) the patients had a body mass index (BMI) more than 25 and less than 39 kg/m2; 6) their weight were stable within three months before present experiment.

Exclusion criteria

Exclusion criteria: 1) the patients had senile dementia, such as Parkinson disease (PD), Alzheimer disease (AD) and brain injury so on; 2) the patients suffered from cardiac disorder, hypertension, dizziness and related disorders; 3) the patients had the obstacle for limb movement; 4) the patients had obvious abnormal clinical findings.

Design outcomes

Primary

MeasureTime frame
inflammatory cytokines;

Countries

China

Contacts

Public ContactLongfeng Sun

The First Affiliated Hospital of China Medical University

sunlf1012@yeah.net+86 13898898686

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026