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Evaluation of changes in skin physiology and appearance after pneumatic injections of non–cross-linked hyaluronic acid in the face

pneumatic injections of non–cross-linked hyaluronic acid in the face

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-17010659
Enrollment
Unknown
Registered
2017-02-17
Start date
2016-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

facial regeneration

Interventions

1: pneumatic injections of non–cross-linked hyaluronic acid in the face

Sponsors

Department of Dermatology, Beijing Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 65 Years

Inclusion criteria

Inclusion criteria: female women aged 35-65 years, WSRS=2, willing to participate; no active skin disease on the face; no oral steroids, collagen powder/liquid, or topical hyaluronic acid used in the last 3 months, no skin-rejuvenation procedure in the last 3 months.

Exclusion criteria

Exclusion criteria: Had hypersensitivity to hyaluronic acid or an active skin disease. Participants were also excluded if they had received oral steroids, collagen powder/liquid, or topical hyaluronic acid in the last 3 months, had undergone a skin-rejuvenation procedure in the last 3 months, were pregnant or breastfeeding, or had severe cardiovascular, cerebrovascular, renal, or hepatic disease.

Design outcomes

Primary

MeasureTime frame
skin hydration;skin transepidermal water loss;skin Melanin index;skin melanin index;skin elasticity;skin texture;skin wrinkle;skin spots;skin pores;—

Countries

China

Contacts

Public ContactLinfeng Li

Beijing Friendship Hospital

zoonli@sina.com+86 13693620186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026