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Minimally invasive surgery plus clot lysis for patients with hypertensive intracranial hemorrhage

A multicenter prospective cohort study to evaluate the effects of minimally invasive surgery plus urokinase thrombolysis in patients with basal ganglia or putaminal hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-16009440
Enrollment
Unknown
Registered
2016-10-15
Start date
2017-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive intracranial hemorrhage

Interventions

Minimally invasive surgery plus clot lysis:Minimally invasive surgery aspiration and postoperative urokinase thrombolysis
open craniotomy:hemotoma evacuation by craniotomy

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) patients who suffered from hypertensive basal ganglia or putaminal hemorrhage with a least volume of 30 mL; (2) admitted within 24 hours after ictus; (3) the Glasgow Coma Scale score of 6 or higher; (4) informed consent is obtained from family members.

Exclusion criteria

Exclusion criteria: (1) Failure to obtain informed consent; (2) Presence of coagulation disorders or thrombocytopenia before surgery; (3) Presence of chronic heart failure, respiratory insufficiency, liver dysfunction or renal impairment before surgery; (4) Patients on oral anticoagulant agents before admission; (5) Pregnancy or breast-feeding women.

Design outcomes

Primary

MeasureTime frame
GOS score at 6-month follow-up;

Secondary

MeasureTime frame
30-day mortality;postoperative intracranial pressure levels;rebleeding incidence;

Countries

China

Contacts

Public ContactLiang Gao

Shanghai Tenth People's Hospital

lianggaohh@163.com+86 13817934652

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026