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Clinical results of gene therapy for granular corneal dystrophy

Clinical results of gene therapy for granular corneal dystrophy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-16008221
Enrollment
Unknown
Registered
2016-04-05
Start date
2016-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

granular corneal dystrophy

Interventions

gene therapy:gene therapy

Sponsors

Eye & ENT Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Be at least 18 years of age, male or female, of any race; 2. Provide written informed consent; 3. Willingness and ability to follow all instructions and comply with schedule for follow-up visits; 4. Diagnosed as granular corneal dystrophy (GCD).

Exclusion criteria

Exclusion criteria: 1. Contraindications to the use of the test article(s); 2. A known allergy to the test article(s) or their components; 3. Current use of any medication due to a psychiatric disorder or cognitive impairment that might affect the psychological assessment; In addition, the Investigator may exclude or discontinue any subject for any sound medical reason.

Design outcomes

Primary

MeasureTime frame
UCDA;BCVA;OCT changes;Aberration;optical quality;biomechanics;contrast sensitivity;genetic test;cytological detection;slit lamp observation;Confocal microscope;—

Countries

China

Contacts

Public ContactXingtao Zhou

Eye & ENT Hospital of Fudan University

doctzhouxingtao@163.com+86 13816880725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026