thalassemia intermedia
Conditions
Interventions
one cohort:combining decitabine and hydroxycarbamide
Sponsors
303rd Hospital of the People`s Liberation Army of China
Eligibility
Sex/Gender
All
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. patients should be diagnosed as thalassemia intermedia by genotype and clinic manifestion; 2. patients should be aged between 16 and 50 yrs old, with ECOG between 0 and 2; 3. Informed consent should be signed before the start of clinic trail.
Exclusion criteria
Exclusion criteria: 1.Any treatment such as blood transfusion, hydroxycarbamide, or yisuishengxue granules in 2 months before including; 2. Pregnancy, breast feeding, or patients in reproductive ages without any measurements of contraception; 3. Patients accompany sever pulmonary or cardiac diseases, liver function abnormal, or sever primary disease of liver, kidney, tumor, and so on; 4. Patients who are allergy to decitabien or hydroxycarbamide; 5. Patients of mental disease; 6. Patients take part in orther kinds of clincic trails in one month; 7. Other conditions that investigaters considered to be not suitable for this clinic trail.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemoglobi; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemoglobine F; | — |
Countries
China
Contacts
Public ContactXiao-lin Yin
303rd Hospital of PLA
Outcome results
None listed