Septic Shock
Conditions
Interventions
one cohort:dobutamine
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
19 Years to 85 Years
Inclusion criteria
Inclusion criteria: having septic shock and ARDS,being on mechanical ventilation with a tidal volume of at least 8 ml/kg without any spontaneous breathing efforts as detected by continuous air-way pressure and flow monitoring on the ventilator screen. The definition for septic shock as defined by the International Sepsis Definitions Conference: 1. Two or more of the following four items: (1) Temperature >38.3 degree C or 4 mmol/L. The definition for ARDS for this investigation was based on the American-European Consensus definition and defined as bilateral infiltrates on the chest radiograph, acute onset of respiratory failure requiring mechanical ventilation, PaO2/FiO2 ratio< 300mm Hg, and a pulmonary artery occlusion pressure 18 mmHg.
Exclusion criteria
Exclusion criteria: 1. Patients were excluded if their chest radiographs were compatible with acute pulmonary oedema, cardiac arrhythmia (atrial fibrillation or frequent premature beats), severe peripheral vascular disease; 2. Hypoxemia caused by congestive heart failure, pulmonary embolism, chronic obstructive pulmonary disease, asthmas and et al.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PICCO;cousumption of blood vessel active drugs;oxygenation index;ventilation free day; | — |
Countries
China
Contacts
Public ContactMin Zhou
Outcome results
None listed