Pancreatic Cancer
Conditions
Interventions
treatment group:external beam radiotherapy
treatment group:chemotherapy with S-1
Sponsors
Zhongshang Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) aged 18-75 years; 2) 3 to 10 weeks after surgical resection; 3) ECOG performance status (PS) 0–2; 4) with 1 or more high risk fators: pT3 or pN1, positive-margin, perineural invasion, Peritumor intravascular cancer emboli; 5) adequate bone marrowhemoglobin:>=110g/L, absolute neutrophil count (ANC)>=1.5*10^9/L, platelet count>=100*10^9/L; 6) kidney function (serum creatinine<=115umol/L) and liver function (serum total bilirubin<=34umol/L).
Exclusion criteria
Exclusion criteria: 1) With distant metastatic disease; 2) With unrecovered postoperative complications; 3) Patients with prior malignancy were ineligible for the study, with the exception of those who had experienced nonmelanoma skin cancer, in situ cancer of the cervix, or other cancer for which the patient had been disease free >=5 yrs. 4) Had received abdominal irradiation before; 5) Poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease-free survival; | — |
Countries
China
Contacts
Public ContactLou Wenhui
Outcome results
None listed