Resistant hypertension
Conditions
Interventions
1:Transcatheter renal denervation
Sponsors
Nil
Eligibility
Sex/Gender
Male
Age
41 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1. Patients office-based systolic blood pressure of 160mmHg or more, despite being treated with at least 3 anti-hypertensive drugs (including on diuretic); 2. Patients must be at least 18 years of age.
Exclusion criteria
Exclusion criteria: 1. Patients not able to give informed consent; 2. Patients with known secondary causes of hypertension; 3. Patients with renovascular abnormalities (including severe renal artery stenosis, previous renal angioplasty or stenting, or known dual renal arteries); 4. Patients who are pregnant; 5. Patients had a glomerular filtration rate (estimated with the modification of diet in renal disease formula) <45ml/min/1.73m2; 6. Patients with type I diabetes mellitus; 7. Patients with haemodynamically significant valvular heart disease, implanted pacemakers or implantable cardioverter defribillators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A composite of adverse events including death, urgent/emergent surgery 30 days after the procedure;A composite of adverse events including renovascular complication 30 days after the procedure;A composite of adverse events including renal failure 30 days after the procedure;A composite of adverse events including the need for blood transfusion 30 days after the procedure;BP measurements at day 1 after the procedure;BP measurements at 1-;3-; 6-; 9- and 12-month after the procedure;Renal function at 3-; 6-; 9- and 12-months; | — |
Countries
China
Contacts
Public ContactProfessor Lam Yat Yin
Outcome results
None listed