Idiopathic nephrotic syndrome
Conditions
Interventions
1:Given methylprednisolone according to the status of the patients
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) >=18years old; (2) Primary nephrotic syndrome and no application of glucocorticoid or immunosuppressive agents; (3) Blood pressure can effectively control less than 130/80mmHg or without hypertension; (4) Taking an ARB or ACEI drugs more than four weeks; (5) Serum creatinine level <=200umol/L; (6) Routine renal biopsy.
Exclusion criteria
Exclusion criteria: (1) All kinds of secondary nephrotic syndrome, such as lupus nephritis, Henoch-Schonlein purpura nephritis, diabetic nephropathy, hypertensive nephropathy and so on; (2) BMI between =25; (3) Urine protein quantitative maitains 0.3-3g/24h after prescription with glucocorticoid 8 weeks; (4) The patients participating the other trials; (5) Researchers consider the patients not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines Level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative remission;Serum creatinine;eGFR;Serum albumin;24h Urine protein quantity; | — |
Countries
China
Contacts
Public ContactXie Hua
Outcome results
None listed