A study for safety andeffecacy of acellular corneal stroma in the treatment of corneal ulcer

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-ONC-12002510

Enrollment

Unknown

Registered

2012-09-12

Start date

2010-04-13

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal ulcer

Interventions

1:acellular corneal stroma

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Both gender aged 18~75 years; 2. To be with corneal ulcer; 3. To be signed the informed consent, agreed to complete treatment andfollow-up.

Exclusion criteria

Exclusion criteria: 1. To be with corneal perforation andexpecting have a vision; 2. To be with severe dry eye; 3. To be with eyes other organic disease; 4. To be with immune corneal diseases; 5. To be with paralysis of corneal ulcer; 6. To be with incomplete eyelid closure; 7. To be with system collagen connective tissue disease; 8. To be with severe allergic constitution; 9. Unble to accept the material due to the reason of religen or culture background; 10. Pregnancy or lactating women as well as who has a birth plan; 11. Liver function (ALT andAST) over than normal two folders; 12. Renal function (Cr) over than normal two folders; 13. To be with severe cardiovascular andcerebral vascular disease; 14. To be with low serum protein; 15. To be with diabetes; 16. To be with tumour; 17. To be involved in other drug or medical instrument clinical trials in last three monthes; 18. To be considered not suitable for this study.

Design outcomes

Primary

Measure	Time frame
Rate of Ulcer healing;	—

Countries

China

Contacts

Public ContactZou Liuhe

zouliuhe@yahoo.com.cn+86 13146273125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026