Esophageal cancer
Conditions
Interventions
Study:Simultaneous modulated accelerated radiation therapy corrent with chemotherapy
Sponsors
Cancer Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) pathological proven diagnosis of primary squamous cell carcinoma of the esophagus; (2) the primary disease located in cervical, upper or middle thoracic esophagus; (3) no distant metastases; (4) Zubrod performance status: 0~2; (5) Age > 18 and 6 months; (7) absence of another malignancy; (8) adequate liver, renal and bone marrow function; (9) women of childbearing potential and male participants must practice adequate contraception; (10) patient must provide study-specific informed consent prior to study entry?
Exclusion criteria
Exclusion criteria: (1) Evidence of tracheoesophageal or Mediastinal-esophageal fistula; (2) Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 2 years; (3) Prior radiation therapy that would result in overlap of planned radiation therapy fields; (4) Severe, active comorbidity; (5) Pregnancy or women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception; (6) Women who are nursing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute toxicities;2-year late toxicitie; | — |
Secondary
| Measure | Time frame |
|---|---|
| 2-year local control rate;2-year overall survival rate; | — |
Countries
China
Contacts
Public ContactChuangzhen Chen
Outcome results
None listed