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Radiotherapy Concurrent with Weekly Nedaplatin for Cervical Carcinoma: Outcomes of a Dose Escalating Study

Radiotherapy Concurrent with Weekly Nedaplatin for Cervical Carcinoma: Outcomes of a Dose Escalating Study

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-12002089
Enrollment
Unknown
Registered
2012-04-06
Start date
2012-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical carcinoma

Interventions

treatment group:Nedaplatin

Sponsors

Affiliated Hospital of Luzhou Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with the pathological diagnosis of cervical cancer; 2. Patients of cervical cancer stage IIb - IVa (according to 2009, FIGO); 3. 20 to 70 years old; 4. Karnofsky score >=70, with weight loss =4.0*10^9/L, neutrophils >=1.5*10^9/L, the PLT >=100*10^9/L, HGB>100g/L; 6. Normal liver and kidney function; 7. Not suffering from other primary cancer and no radiotherapy and chemotherapy in 5 years; 8. No distant metastasis by examination of MRI, CT, chest X-ray and B ultrasonic imaging; 9. No other serious comorbidities such as hypertension, tuberculosis and type 2 diabetes, etc; 10. Not in pregnancy or lactation.

Exclusion criteria

Exclusion criteria: (1) The patients ask to quit; (2) The course of treatment is extended for more than one week by other reasons; (3) Adverse reactions beyond the dose-limited toxicity, can not be reversed by symptomatic treatment; (4) Patients combined with neuropsychiatric diseases.

Design outcomes

Primary

MeasureTime frame
Adverse Events;dose-limiting toxity;curative effect;

Countries

China

Contacts

Public ContactYang hong-ru
yanghongru801@126.com+86 15181416760

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026