Heart Failure
Conditions
Interventions
Case series:NA
Sponsors
Dept of Medicine & Therapeutics, CUHK
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with HF due to systolic dysfunction who are suitable candidates for CRT according to the current Patients with HF due to systolic dysfunction who are suitable candidates for CRT according to the current ACC/AHA/ESC guidelines will be enrolled, namely, patients with NYHA class III or IV, ejection fraction 120ms, and refractory to optimal medical therapy including neurohormonal blockers; Patients with atrial fibrillation are accepted for CRT from current guideline and hence will be induced. However, measures will be taken to ensure a high percentage of biventricular pacing (e.g. aggressive beta-blockers, digoxin etc).
Exclusion criteria
Exclusion criteria: 1. HF with LV ejection fraction > and = 35%; 2. Any major illnesses with life expectancy <6months, e.g., terminal malignancy; 3. Patients unwilling to participate into the study or refuse or deemed unsuitable for CRT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To develop and validate a comprehensive clinical model with a scoring system that will increase the response rate of CRT; | — |
Secondary
| Measure | Time frame |
|---|---|
| To improve the overall response rate of CRT from primarily a clinical perspective to secondarily a cardiac functional perspective; | — |
Countries
China
Contacts
Public ContactCheuk-Man YU
Outcome results
None listed