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Estimation of the warfarin dosage with clinical and pharmacogenetic data for Chinese patients

Estimation of the warfarin dosage with clinical and pharmacogenetic data for Chinese patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-11001532
Enrollment
Unknown
Registered
2011-07-16
Start date
2011-03-16
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who need to take warfarin, including prothetic heart valve replacement, atrial fibrilation, deep vein thrombosis, pulmanory ebolism, stroke.

Interventions

Total:genotype analysis

Sponsors

Institute of Clinical Pharmacology, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Chinese origin, both male and female, age unlimited; 2) Patients who need to take warfarin for 6 months and under regular PT-INR examination between January 1, 2008 and June 31, 2013. Indications include heart valve replacement, atrial fibrillation, deep vein thrombosis, pulmanory ebolism, stroke; 3) have signed informed consent, and agree to participant the project; 4) good compliance, follow up for at least 6 month.

Exclusion criteria

Exclusion criteria: 1) bad compliance, stop following up for at least 3 consecutive visits or do not take warfarin as indicated; 2) have cancer; 3) pregnant or lactating; 4) have contraindication of warfarin.

Design outcomes

Primary

MeasureTime frame
stable warfarin dosage;

Countries

China

Contacts

Public ContactZhi Li
lizhi489@163.com+86 731 84805380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026