atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA), pulmonary stenosis (PS), mitral stenosis (MS)
Conditions
Interventions
MS group:interventional therapy
PDA group:interventional therapy
ASD group:interventional therapy
VSD group:interventional therapy
PS group:interventional therapy
Sponsors
Guangdong Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 65 Years
Inclusion criteria
Inclusion criteria: Retrospective study:Cases of continuous interventional treatment before December 31, 2007, including the success and failure cases, no matter how long the follow-up time it is. Prospective study: Cases of intervention treatment during January 2008 to December 2010 with the following conditions: 1-ASD: 1) Ostium secundum defect with the evidence of right ventricular volume overload; 2) ASD reserved after surgery; 3) Ostium secundum defect with residual shunt after surgery; 4) Diameter of defect >=5mm, =6.67kpa (50mmHg); 2) Typical pulmonary stenosis. ECG show the enlargement of right ventricular. And its imaging show the Pulmonary artery expansion. The different pressure between the both side of the pulmonary valve is 4.67-6.67kpa (35-50mmHg). 5-MS: 1) Rheumatic mitral stenosis patient definited by clinical diagnoses; 2) Mitral valve area <=1.5cm2; 3) Wilkins ultrasound scoring <=8; 4) Degree of mitral regurgitation is below class II. (Colour Doppler Echocardiography); 5) Combine with aortic regurgitation: below class II(Colour Doppler Echocardiography); 6) No aortic valve stenosis; 7) No active rheumatic; 8) NYHA class II ~ IV (Cardiac function); 9) Patients with atrial fibrillation but without left ventricular thrombus proved by Transesophageal Echocardiogram (TEE).
Exclusion criteria
Exclusion criteria: Retrospective study: Cases of continuous intervention before December 31, 2007, combine with the other abnormality at the same time. Prospective study: Cases of interventional treatment during January 2008 to December 2010 with the following conditions: 1-ASD 1) Ostium secundum defect with other congenital cardio-abnormality which require a surgical correction. 2) Ostium secundum defect combine with other congenital cardio-abnormality for the interventional treatment at the same time. 3) Venous sinus type ASD 4) Severe pulmonary hypertension causes right to left shunt 5) Routine cardiac catheterization can not be tolerated. 2-VSD 1) weight8 6) Patient combine with early pregnancy (<3 months) 7) Patient combine with other congenital cardiovascular malformations 8) Patient combine with other serious organ dysfunction except the heart. 9) Combine with other heart malformation such as: dextrocardia or significant scoliosis .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ASD Safety: No deaths or serious complications;PDA: Evaluate the efficacy by PDA imaging;PS Safety;MS safety;PDA: Evaluate the efficacy by PDA echocardiogram;PDA Safety: No deaths or serious complications;PS efficacy;MS efficacy;VSD: Evaluate the efficacy by VSD imaging;VSD: Evaluate the efficacy by VSD echocardiogram;VSD Safety: No deaths or serious complications;ASD Efficacy: ASD closure is successful or no; | — |
Countries
China
Contacts
Public ContactShuguang LIN
Outcome results
None listed