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The clinical application of rituximabin in treatment of refractory nephrotic syndrome in children

The clinical application of rituximab in treatment of refractory nephrotic syndrome in children

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-10001125
Enrollment
Unknown
Registered
2010-12-04
Start date
2011-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

refractory nephrotic syndrome in children

Interventions

1:rituximab 375mg/m2

Sponsors

Nanjing General hospital of Nanjing militray command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children with refractory nephrotic syndrome and unsensitive to other medicine

Exclusion criteria

Exclusion criteria: Patients who are allergic to rituximab or mouse protein

Design outcomes

Primary

MeasureTime frame
CD8;CD20;CD4;CD19;CD3;

Secondary

MeasureTime frame
immunoglobulin;B lymphocyte count;liver and kidney function;blood routine test;renal pathology;

Countries

China

Contacts

Public ContactZhengkun Xia
njxzk@126.com+86 025 80861386

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026