type 2 diabetes
Conditions
Interventions
treatment group:Umbilical cord mesenchymal stem cell transplantation
Sponsors
Armed Police General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. the patients were between the ages of 18 and 70 years, male or female; 2. they had poor blood control with recent anti-diabetic therapies, including drugs and/or insulin injection for at least three months; 3. they had a negative result in testing for the glutamic acid decarboxylase antibody; 4. they had not been pregnant or nursing; 5. they had a fasting blood glucose (FBG) level >=7.0 mmol/L and HbAc1>=7%; 6. they had a good organic sufficiency, including heart, liver, kidney and lung, to receive interventional therapy.
Exclusion criteria
Exclusion criteria: 1. cancer; 2. serious heart disease or hypertension; 3. acute and chronic renal insufficiency or liver failure; 4. severe asthma or other severe respiratory insufficiency; 5. hemorrhagic disease, coagulopathy, contrast agent allergy or are being applied anticoagulant drugs; 6. congenital or acquired immunodeficiency diseases; 7. other endocrine and metabolic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood sugar;Glycated hemoglobin;Islet function;Inflammatory cytokines (IL-1beta, IL-6, IL-10 and TNF-alpha); | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral blood T lymphocyte subset count;C peptid; | — |
Countries
China
Contacts
Public ContactYihua An
Outcome results
None listed