Healthy Volunteers
Conditions
Interventions
Only one group:~1 ml blood were taken from an antecubital vein catheter at 0, 0.5, 1.5, 3, 4.5, 8, 12, 15, 25, 30, 38, and 49 h after oral adminisrateion of Panax notoginseng extract at 35 ml/subject.
Sponsors
Shanghai Institute of Materia Medica, Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
21 Years to 29 Years
Inclusion criteria
Inclusion criteria: (1) Healthy human subjects between 20 to 30 years old with body mass index not exceeding the ideal value more than 15%; (2) Subjects must understand the purpose, character, procedures of the pharmacokinetic study, as well as the characteristics of Panax notoginseng extract. Subject should participate in the study of his own accord and sign Informed Consent Form prior to this study.
Exclusion criteria
Exclusion criteria: (1) Subjects who took any over-the-counter or prescription drugs within two weeks or any alcohol-, caffeine-, tea-, or citrus-containing beverages or foods within two days; (2) Subjects who participated any investigational drug study within 3 months prior to this study; (3) In the opinion of the investigator, subjects who are not suitable to participate in the study for whatever reasons must be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drug concentration in urine;Drug concentration in blood; | — |
Contacts
Public ContactChuan Li
Outcome results
None listed