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Identification of genes for high myopia

Identification of genes for high myopia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ONC-05000675
Enrollment
Unknown
Registered
2005-12-13
Start date
2004-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

case series:Nil

Sponsors

Nil
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
1 Years to 90 Years

Inclusion criteria

Inclusion criteria: Plan to carry out whole genome scan and linkage studies of 30 independent pedigrees of at least 3 generations, each with more than 10 members and 3 high myopia that we have recruited. None of these families have myopia associated disease such as Stickler's syndrome, Marfan syndrome and juvenile glaucoma.

Exclusion criteria

Exclusion criteria: Subjects with known or suspected medical disorders or ocular complications other than those described

Design outcomes

Primary

MeasureTime frame
Advancing knowledge in basic molecular genetics.;

Secondary

MeasureTime frame
1. Affirm chromosomal loci linked to myopia. 2. Identify new myopia genes. 3. Reveal the frequencies of specific sequence alterations in the new putative myopia gene(s) in the local Chinese population. 4. Establish a basis to study interactive effects between environmental and genetic factors that contribute to myopia.;

Countries

China

Contacts

Public ContactProf. Dennis SC Lam
dennislam_cu_res@cuhk.edu.hk+852 2762 3134

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026