Gynecological tumor and rectum cancer
Conditions
Interventions
Rectum cancer group:pelvic functional bone marrow's dose-volume parameter's limits
gynecological cancer group:pelvic functional bone marrow's dose-volume parameter's limits
Sponsors
Jiangmen Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for rectum cancer: 1) pathological confirmation, clinical stage II and III,patients needing preoperative chemoradiotherapy or postoperative chemoradiotherapy but without pretreatment radiotherapy; 2) aged 18 to 80 years, PS 0-2; 3) normal liver and kidney function; 4) normal bone marrow function: Hb >10 g/dl, neutrophil cells= 2000/ul, WBC = 4000/ul,PLT = 100,000/ul; 5) all patients signed the informed consent of chemoradiotherapy. Inclusion criteria for cervical cancer/endometrial cancer: 1) pathological confirmation, clinical stage IB to IVa, patients needing radical chemoradiotherapy or those who have some bad prognostic factors and need postoperative chemoradiotherapy; 2) All patients should not have any pretreatment radiotherapy before concurrent chemoradiotherapy; 3) aged 18 to 80 years, PS 0-2; 4) normal liver and kidney function; 5) normal bone marrow function: Hb >10 g/dL,neutrophil cells= 2000/ul, WBC = 4000/ul, PLT = 100,000/ul; 6) all patients signed the informed consent of radiotherapy.
Exclusion criteria
Exclusion criteria: Exclusion criteria for rectum cancer: 1) Patients once received pelvic pretreatment radiotherapy before concurrent chemoradiotherapy; 2) Patients with severe comorbidities which make them not tolerate any chemoradiotherapy; 3) Patients with severe obstructive disease. Exclusion criteria for cervical cancer/endometrial cancer: 1) Patients need para-aortic radiotherapy; 2) Patients once received pelvic pretreatment radiotherapy before concurrent chemoradiotherapy; 3) Patients with severe comorbidities which make them not tolerate any chemoradiotherapy; 4) Patients with severe obstructive disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional bone marrow 1 and functional bone marrow 2's parameters of dose and volume;hematological toxicity during chemoradiotherapy; | — |
Countries
China
Contacts
Public ContactXiao Lin
Jiangmen Central Hospital
Outcome results
None listed