several common malignant tumors
Conditions
Interventions
Case series:vaccines from tumor cell membrane protein
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) signed the informed consent; 2) Aged 18 to 70 years old; 3) After surgery, HEKT cells were further removed. Pathological diagnosis of lung adenocarcinoma, lung small cell carcinoma, hepatocellular carcinoma and pancreatic cancer, colorectal cancer, breast cancer; 4) Peripheral white blood cell count> 3×10^9/L; lymphocyte absolute> 1.0×10^9/L; lymphocyte ratio> 18%; 5) all tumor molecular markers are normal; The general condition of the patient may survive for more than 3 months.;Inclusion criteria: 1) signed the informed consent; 2) Aged 18 to 70 years old; 3) After surgery, HEKT cells were further removed. Pathological diagnosis of lung adenocarcinoma, lung small cell carcinoma, hepatocellular carcinoma and pancreatic cancer, colorectal cancer, breast cancer; 4) Peripheral white blood cell count> 3×10^9/L; lymphocyte absolute> 1.0×10^9/L; lymphocyte ratio> 18%; 5) all tumor molecular markers are normal; The general condition of the patient may survive for more than 3 months.;Inclusion criteria: 1) signed the informed consent; 2) Aged 18 to 70 years old; 3) After surgery, HEKT cells were further removed. Pathological diagnosis of lung adenocarcinoma, lung small cell carcinoma, hepatocellular carcinoma and pancreatic cancer, colorectal cancer, breast cancer; 4) Peripheral white blood cell count> 3×10^9/L; lymphocyte absolute> 1.0×10^9/L; lymphocyte ratio> 18%; 5) all tumor molecular markers are normal; The general condition of the patient may survive for more than 3 months.;Inclusion criteria: 1) signed the informed consent; 2) Aged 18 to 70 years old; 3) After surgery, HEKT cells were further removed. Pathological diagnosis of lung adenocarcinoma, lung small cell carcinoma, hepatocellular carcinoma and pancreatic cancer, colorectal cancer, breast cancer; 4) Peripheral white blood cell count> 3×10^9/L; lymphocyte absolute> 1.0×10^9/L; lymphocyte ratio> 18%; 5) all tumor molecular markers are normal; The general condition of the patient may survive for more than 3 months.;Inclusion criteria: 1) signed the informed consent; 2) Aged 18 to 70 years old; 3) After surgery, HEKT cells were further removed. Pathological diagnosis of lung adenocarcinoma, lung small cell carcinoma, hepatocellular carcinoma and pancreatic cancer, colorectal cancer, breast cancer; 4) Peripheral white blood cell count> 3×10^9/L; lymphocyte absolute> 1.0×10^9/L; lymphocyte ratio> 18%; 5) all tumor molecular markers are normal; The general condition of the patient may survive for more than 3 months.
Exclusion criteria
Exclusion criteria: 1) T cell lymphoma, syphilis, AIDS patient or cohort; 2) a high degree of allergies or a history of severe allergies; 3) severe liver and kidney dysfunction; 4) patients with severe autoimmune diseases or who are receiving immunosuppressive therapy; 5) serious infection without control or high fever; 6) organ transplants or intended organ transplants; 7) brain metastases and macrovascular invasion; 8) shock, vital organ failure, vital signs of unstable patients; 9) severe coagulopathy (such as hemophilia); 10) Consolidated mental or mental illness can not be matched with treatment and efficacy assessment; 11) women of childbearing age during pregnancy, lactating women, or refusal to use contraceptive measures during the study; 12) Drug or alcohol abusers; 13) Doctors think there are other reasons that can not be included in the treatment.;Exclusion criteria: 1) T cell lymphoma, syphilis, AIDS patient or cohort; 2) a high degree of allergies or a history of severe allergies; 3) severe liver and kidney dysfunction; 4) patients with severe autoimmune diseases or who are receiving immunosuppressive therapy; 5) serious infection without control or high fever; 6) organ transplants or intended organ transplants; 7) brain metastases and macrovascular invasion; 8) shock, vital organ failure, vital signs of unstable patients; 9) severe coagulopathy (such as hemophilia); 10) Consolidated mental or mental illness can not be matched with treatment and efficacy assessment; 11) women of childbearing age during pregnancy, lactating women, or refusal to use contraceptive measures during the study; 12) Drug or alcohol abusers; 13) Doctors think there are other reasons that can not be included in the treatment.;Exclusion criteria: 1) T cell lymphoma, syphilis, AIDS patient or cohort; 2) a high degree of allergies or a history of severe allergies; 3) severe liver and kidney dysfunction; 4) patients with severe autoimmune diseases or who are receiving immunosuppressive therapy; 5) serious infection without control or high fever; 6) organ transplants or intended organ transplants; 7) brain metastases and macrovascular invasion; 8) shock, vital organ failure, vital signs of unstable patients; 9) severe coagulopathy (such as hemophilia); 10) Consolidated mental or mental illness can not be matched with treatment and efficacy assessment; 11) women of childbearing age during pregnancy, lactating women, or refusal to use contraceptive measures during the study; 12) Drug or alcohol abusers; 13) Doctors think there are other reasons that can not be included in the treatment.;Exclusion criteria: 1) T cell lymphoma, syphilis, AIDS patient or cohort; 2) a high degree of allergies or a history of severe allergies; 3) severe liver and kidney dysfunction; 4) patients with severe autoimmune diseases or who are receiving immunosuppressive therapy; 5) serious infection without control or high fever; 6) organ transplants or intended organ transplants; 7) brain metastases and macrovascular invasion; 8) shock, vital organ failure, vital signs of unstable patients; 9) severe coagulopathy (such as hemophilia); 10) Consolidated mental or mental illness can not be matched with treatment and efficacy assessment; 11) women of childbearing age during pregnancy, lactating women, or refusal to use contraceptive measures during the study; 12) Drug or alcohol abusers; 13) Doctors think there are other reasons that can not be included in the treatment.;Exclusion criteria: 1) T cell lymphoma, syphilis, AIDS patient or cohort; 2) a high degree of allergies or a history of severe allergies; 3) severe liver and kidney dysfunction; 4) patients with severe autoimmune diseases or who are receiving immunosuppressive therapy; 5) serious infection without control or high fever; 6) organ transplants or intended organ transplants; 7) brain metastases and macrovascular invasion; 8) shock, vital organ failure, vital signs of unstable patients; 9) severe coagulopathy (such as hemophilia); 10) Consolidated mental or mental illness can not be matched with treatment and efficacy assessment; 11) women of childbearing age during pregnancy, lactating women, or refusal to use contraceptive measures during the study; 12) Drug or alcohol abusers; 13) Doctors think there are other reasons that can not be included in the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS;OS; | — |
Countries
China
Contacts
Public ContactZeqiang Zhou;Zeqiang Zhou;Zeqiang Zhou;Zeqiang Zhou;Zeqiang Zhou ;;;;
;;;;
Outcome results
None listed