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A Multicenter Prospective Study of the extended-field Intensity Modulated Radiation Therapy With Concurrent chemotherapy and Brachytherapy for Cervical Cancer

A Multicenter Prospective Study of the extended-field Intensity Modulated Radiation Therapy With Concurrent chemotherapy and Brachytherapy for Cervical Cancer

Status
Recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OIC-17011347
Enrollment
Unknown
Registered
2017-05-11
Start date
2016-08-01
Completion date
Unknown
Last updated
2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

observation group:Concurrent chemoradiotherapy

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Pathological diagnosis of cervical cancer; 2. ECOG =2; 3. Aged from 18 to 70 years; 4. Imaging digonised or pathological diagonised Para aortic lymph node or Common iliac artery lymph node metastasis; 5. FIGO stages IB-IIIB with or without para arotic lymph node metastasis; 6. no other distant metasitasis; 7. without any other cancer; 8. never received radiotherapy or chemotherapy; 9. WBC=3.5×10^9/L; NEUT=2×10^9/L; HGB=90g/dL; PLT=100×10^9/L; Cr<1.5mg/dlALT<100u/L.

Exclusion criteria

Exclusion criteria: 1. refuse Concurrent chemoradiotherapy; 2. cannt afford Concurrent chemoradiotherapy; 3. cannt not to do intracavitary brachytherapy; 4. find distant metastasis during the treatment.

Design outcomes

Primary

MeasureTime frame
evaluated the acute toxic reactions for the patients who diagnosed cervical cancer with Para aortic lymph node or Common iliac artery lymph node metastasis and received extended-field IMRT plus concurrent chemotherapy plus brachytherapy;evaluated the chronic toxic reactions for the same patients;

Secondary

MeasureTime frame
evaluated the clinical efficacy, such as overall survival rate, tumor free survival rate, Pelvic recurrence rate, para-aortic recurrence rate and non-para aortic metastasis rate etc.;

Countries

China

Contacts

Public ContactHu Ke

Peking Union Medical College Hospital

huke8000@163.com+86 13911509719

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026