Effects of artificial tears to the patients with dry eye on the measurement of corneal biology

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OIC-17011111

Enrollment

Unknown

Registered

2017-04-10

Start date

2018-01-04

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry-eye syndrome

Interventions

group A:Group A , 30eyes, the patients with dry eye of level 1 before surgery were measured corneal curvature, astigmatism,Q value, SRI and SAI, IAI and PVA before dripping with 0.1% hyaluronic acid s

group B:Group B , 30eyes, the patients with dry eye of level 2 before surgery were measured corneal curvature, astigmatism,Q value, SRI and SAI, IAI and PVA before dripping with 0.1% hyaluronic acid s

group C:Group C , 30eyes, the patients with dry eye of level 1 before surgery were measured corneal curvature, astigmatism,Q value, SRI and SAI, IAI and PVA before dripping with 0.3% hyaluronic acid s

group D:Group D , 30eyes, the patients with dry eye of level 2 before surgery were measured corneal curvature, astigmatism,Q value, SRI and SAI, IAI and PVA before dripping with 0.3% hyaluronic acid

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Hospitalized elderly patients with cataract, aged between 50 and 80 years; subjects were informed and voluntarily accepted the examination and treatment.

Exclusion criteria

Exclusion criteria: Exclude disease of conjunctivitis, keratitis or glaucoma; exclude the history disease of lacrimal apparatus diseases, laser eye or other eye surgery; exclude ocular trauma history; other systemic disease which effect tear secretion; exclud the patients who are using artificial tears and other drugs which effect the ocular surface function within six months; exclud the patients with large irregular astigmatism.

Design outcomes

Primary

Measure	Time frame
first noninvasive tear film break-up time;average noninvasive tear film break-up time;irregularity;Q value;corneal curvature;corneal astigmatism;Surface Regularity Index;Surface Asymmetry Index;Irregular astigmatism index;PVA;	—

Contacts

Public ContactJinsong Zhang

Ophthalmologic hospital of China Medical University;The Fourth Affiliated Hospital of China Medical University

cmu4h-zjs@126.com+86 18900916888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026