Sequential chemoradiotherapy followed by surgical resection for locally advanced thymic tumors

Status

Recruiting

Phases

Phase 2

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OIC-16009130

Enrollment

Unknown

Registered

2016-08-31

Start date

2015-08-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thymic tuors

Interventions

1:induction chemotherapy (TPx2)

1:induction radiotherapy (40Gy)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. diagnosed as thymic tumor by pre-treatment biopsy; 2. locally invasive tumors defined by radiographic images (including stage IV cases whose pleural nodules or lymphnoeds are adjacent to mediastinal tumors); 3. cardiac and pulmonary function, as well as hepatic and renal fuction are good enough to tolerate surgery; 4. KPS score is better than 80.

Exclusion criteria

Exclusion criteria: 1. extensive stage 4 disease; 2. allergic to chemotherapy drugs (paclitaxel, carboplatin); 3. can not tolerate surgery; 4. in pregnancy.

Design outcomes

Primary

Measure	Time frame
response rate;	—

Secondary

Measure	Time frame
complete resection rate;five year survival rate;	—

Countries

China

Contacts

Public ContactFang Wentao

Shanghai Chest Hospital, Shanghai Jiaotong University

vwtfang@hotmail.com+86 18017321389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026