Healthy subjects
Conditions
Interventions
two:Reference and controlled drugs
Sponsors
Clinical Pharmacology Institution, Central South University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. healthy volunteers, 18 ~ 40 years old, including boundary value;With the group of age are not more than 10 years apart; 2. greater than 50 kg weight, body mass index (BMI) subjects between 19 and 24 kg/m2, including boundary value, with batch weight difference should not be different; 3. physical examination without exception discoverer; 4. there is no history of drug allergy; 5. a smoke-free, alcohol hobby; 6. subjects volunteered for the experiment and is willing to test in accordance with the provisions of this test procedure; 7. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. within 4 weeks before test had clinical significance of the disease or received surgery; 2. any existing laboratory results of clinical significance of abnormal situation; 3. used within three months of a known viscera damage drugs or drugs currently in use; 4. has a history of drug allergy and highly sensitive to the environment material;Of salvia miltiorrhiza and allergy to any ingredient or drugs; 5. was susceptible to disease of hypokalemia; 6. congestive heart failure, gastric ulcer, glucose - 6 - phosphate dehydrogenase (G6PD) deficiency, severe liver function damage, severe kidney damage; 7. any other clinical history of severe disease or cardiovascular system, endocrine system, nervous system disease or lung, hematology, immunology, history of psychiatric disease and metabolic abnormalities, etc; 8. recent cold; 9. with active bleeding, diseases such as diabetes, glaucoma; 10. testing positive for HIV; 11. test positive for hepatitis b surface antigen or hepatitis c testing positive for; 12. are associated with treatment of any medical significance, the 13. to attend within 14 days before the test is associated with people; 14. has a history of drug abuse; 15. during 3 months before the test and test taking soft drugs (such as marijuana) or test a year before and during the test to take hard drugs (such as cocaine, benzene piperidine, etc.); 16. participants attended other drugs within three months; 17. test before 3 months to participate in blood donors; 18. with blood coagulation dysfunction or thromboembolic disorders. 19. The stomach is cold.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| medicine generation power curve; | — |
Countries
China
Contacts
Public Contactzhirong Tan
Clinical Pharmacology Institution, Central South University
Outcome results
None listed