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Efficacy and safety of rapamycin in the treatment of kaposiform hemangioendothelioma in infants

Efficacy and safety of rapamycin in the treatment of kaposiform hemangioendothelioma in infants

Status
Recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OIC-16008525
Enrollment
Unknown
Registered
2016-05-24
Start date
2016-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kaposiform hemangioendothelioma

Interventions

Sponsors

Guang Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients must be diagnosed as kaposiform hemangioendothelioma by clinical, radiographic or histologic criteria; The lesion is cuticuar superficial; Enrollment include patients of both genders; Patients must be 0-4 years of age at the time of study entry; The patient's parents must assign the consent about the therapy of oral rapamycin.

Exclusion criteria

Exclusion criteria: Known history of known immunodeficiency such as HIV; Concurrent severe and/or uncontrolled medical disease which could compromise participation in the study (e.g. uncontrolled diabetes, uncontrolled hypertension, severe infection,severe malnutrition, chronic liver or renal disease); Impairment of gastrointestinal functiono or gastrointestinal disease that maysignificantly alter the absorption of rapamycin.

Design outcomes

Primary

MeasureTime frame
Average time to initial response;Average stablization time of platelet;Average time of rapamycin treatment;Average time for rapamycin treated as a single agent;

Countries

China

Contacts

Public ContactZhang Jing

Guang Women and Children's Medical Center

fejr@foxmai.com+86 13826282846

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026