kaposiform hemangioendothelioma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients must be diagnosed as kaposiform hemangioendothelioma by clinical, radiographic or histologic criteria; The lesion is cuticuar superficial; Enrollment include patients of both genders; Patients must be 0-4 years of age at the time of study entry; The patient's parents must assign the consent about the therapy of oral rapamycin.
Exclusion criteria
Exclusion criteria: Known history of known immunodeficiency such as HIV; Concurrent severe and/or uncontrolled medical disease which could compromise participation in the study (e.g. uncontrolled diabetes, uncontrolled hypertension, severe infection,severe malnutrition, chronic liver or renal disease); Impairment of gastrointestinal functiono or gastrointestinal disease that maysignificantly alter the absorption of rapamycin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average time to initial response;Average stablization time of platelet;Average time of rapamycin treatment;Average time for rapamycin treated as a single agent; | — |
Countries
China
Contacts
Guang Women and Children's Medical Center