refractive error with thin cornea, cornea pathology, keratoconus
Conditions
Interventions
1:lenticule transplantation with small incision lenticule extraction (SMILE)
Sponsors
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Be at least 18 years of age, male or female, of any race; 2. Provide written informed consent; 3. Willingness and ability to follow all instructions and comply with schedule for follow-up visits; 4. Diagnosed as refractive error with thin cornea, cornea pathology, or keratoconus; 5. Contact Lens Wearers Only: Removal of contact lenses for the required period of time prior to the screening refraction: Contact Lens Type Minimum Discontinuation TimeSoft 1 WeekSoft Extended Wear 1 WeekSoft Toric 2 Weeks Rigid gas permeable 2 Weeks.
Exclusion criteria
Exclusion criteria: 1. current use of any medication due to a psychiatric disorder or cognitive impairment that might affect the psychological assessment; 2. subjects who had undergone ocular surgery within the last 6 months; 3. Pregnancy (including plans to become pregnant) or lactation during the course of the study; 4. Patients with nystagmus or any other condition that would prevent a steady gaze during the treatment or other diagnostic tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| efficacy index;safety index;biomechanics;slit lamp observation;Confocal microscope;OCT observation;corneal structure changes;optical quality;contrast sensitivity;corneal sensitivity; | — |
Countries
China
Contacts
Public ContactXingtao Zhou
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry
Outcome results
None listed