Alzheimer's Disease
Conditions
Interventions
all participants:sleep deprivation
Sponsors
the First Affliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Healthy men and women of non-childbearing potential, 18 to 45 years of age inclusive, signing concent form; (2) the Pittsburgh sleep quality index scale(PSQI), show that well sleep quality, regular sleep habits, normal sleep/wake cycle, sleep no later than 1 PM every night, no early to get up before 6 o 'clock in the morning. sleep 6-9 hours each night on average, without too much sleep during the day or insomnia and other sleep disorders; (3) Normal liver and renal function.
Exclusion criteria
Exclusion criteria: (1) history of acute infection or symptoms of infection Recently in 2 weeks; (2) work in shifts or night duty; (3) history of any neurologic or psychiatric illness including drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum Aß; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum ROS;serum NE; | — |
Countries
China
Contacts
Public ContactMeng Wei
Outcome results
None listed