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Comparation of the influence of lumbar plexus-sciatic nerve block and spinal anesthesia on early postoperative cognitive dysfunction (POCD) in elderly patients with upper femur fracture – and the correlation study between POCD and intraoperative hemodynamic status.

Comparation of the influence of lumbar plexus-sciatic nerve block and spinal anesthesia on early postoperative cognitive dysfunction (POCD) in elderly patients with upper femur fracture – and the correlation study between POCD and intraoperative hemodynamic status.

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OIC-16007843
Enrollment
Unknown
Registered
2016-01-27
Start date
2016-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction

Interventions

Anesthesia methods:Anesthesia methods

Sponsors

Ningbo 2nd Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: Elderly patients scheduled to undergo unilateral proximal femoral surgery (hip hemiarthroplasty, total hip arthroplasty, and intertrochanteric fracture surgery) during lumbar plexus-sciatic nerve block or spinal anesthesia, aged 65-90 years, BMI 18-28 kg/m2, ASA I-III, signed informed consent form for anesthesia and the study.

Exclusion criteria

Exclusion criteria: Mini-Mental State Examination (MMSE) score <=23; NYHA class III-IV; History of cardiac or thoracic surgery; Pre-existing neurological or mental disease; Severe liver or kidney function damage; Anticipated difficulty with neuropsychological assessment; Failed to complete the assessment; Contraindications to lumbar plexus-sciatic nerve block or spinal anesthesia.

Design outcomes

Primary

MeasureTime frame
MMSE score at 7 days after operation;—

Countries

China

Contacts

Public ContactGuorong Wu
13600628721@163.com+86 13600628721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026