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The effection of a low dose of naloxone added to ropivacaine or sufentanil-ropivacaine for brachial plexus anesthesia

The effection of a low dose of naloxone added to ropivacaine or sufentanil-ropivacaine for brachial plexus anesthesia

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OIC-15007434
Enrollment
Unknown
Registered
2015-11-22
Start date
2015-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb surgery

Interventions

control group:20ml(0.375%)ropivacaine
sufentanil:20ml(0.375%)ropivacaine+10vg sufentanil
naloxone:20ml(0.375%)ropivacaine+100ng naloxone
naloxone combined with sufentanil:20ml(0.375%)ropivacaine+10vg sufentanil+100ng naloxone

Sponsors

The First Affiliated Hospital of Xinjiang Shihezi University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient participant requirements included a body mass index (BMI) of less than 30 kg/m2, an ASA physical status class I and II,and being scheduled for elective forearm and arm surgery (<180 min) under brachial plexus block.

Exclusion criteria

Exclusion criteria: Patients with a history of study protocol drug allergy, significant hepatic or renal disease, coagulation disorder, infection at the puncture site, pregnant women, or individuals with an addiction to benzodiazepines,clonidine, cocaine, or opioids were not included in the study. Patients with any intraoperative complication, unsuccessful block, or prolonged surgery (> 180 min) were excluded.

Design outcomes

Primary

MeasureTime frame
duration of sensory block;

Secondary

MeasureTime frame
duration of motor block,;

Countries

China

Contacts

Public ContactXiwei Dong
dede123@163.com+86 13899534304

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026