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Brain-specific proteins in pediatric patients with encephalitis and the predictive values for adverse outcomes of the central nervous system

Brain-specific proteins in pediatric patients with encephalitis and the predictive values for adverse outcomes of the central nervous system

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCS-14004803
Enrollment
Unknown
Registered
2014-06-16
Start date
2014-06-23
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

encephalitis in children

Interventions

Case series:NA

Sponsors

The Affiliated Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Patients aged from 0-18 years with symptoms suggestive of encephalitis would be actively recruited.The case definition included any person of any age admitted to hospital with encephalopathy (altered consciousness that persistedforlonger than 24h, including lethargy, irritability, or a change in personality and behaviour) and with two or more of the following: fever or history of fever (=38 degree C) during the presenting illness; seizures and/or focal neurological findings (with evidence of brain parenchyma involvement); CSF pleocytosis (more than four white blood cells per µL); electroencephalographic (EEG) findings indicative of encephalitis; and abnormal results of neuroimaging (CT or MRI) suggestive of encephalitis.

Exclusion criteria

Exclusion criteria: Any patients with a history fo brain trauma, intracranial hemorrhage,congenital brain abnormalities, heritage metabolic disease,anoxic ischemic encephalopathyc,cerebral dysplasia and toxic encephalopathy.

Design outcomes

Primary

MeasureTime frame
Glasgow coma scale;Glasgow outcome scale;

Contacts

Public ContactNing Fu

Laboratory of Emerging Infectious Disease and Division of Laboratory Medicine, the Affiliated Zhujiang Hospital of Southern Medical University

zfzn@smu.edu.cn+86 13662520606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026