severe sepsis
Conditions
Interventions
Sponsors
the Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: age 18 years or older; has a confirmed or highly suspected infection consistent with severe sepsis; has two or more of the following: core temperature > 38.3°C or 90/min, Acute lung injury with PaO2/FiO2 12,000 µL–1or 4000µL–1, Platelet count?2.0 mg/dL (176.8umol/L),has norepinephrine after adequate fluid resuscitation at a dose of at least 0.1ug/kg/min to maintain systolic blood pressure above 90 mmHg.
Exclusion criteria
Exclusion criteria: patients with vascular disease,such as arteriosclerosis,systemic vasculitis,thrombotic diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| syndecan-1;angiopoietins -1;sTM;soluble Intercellular Adhesion Molecular-; | — |
Countries
China
Contacts
Public ContactWu Xinhui
Outcome results
None listed