Chronic Kidney Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with CKD (stage 3?5) (eGFR=60ml/min/1.73m2) including patients on hemodialysis and peritoneal dialysis (stage 5D); 2.patients with capability to read and write;3.patients have received the standard CKD management according to the guideline at least 3 months;4.patients with stable clinical status;5.Age: 18-75 years;6.Patients with normal diet through the mouth;7.Patients with informed consent form signed.
Exclusion criteria
Exclusion criteria: 1.Patients after renal transplantation; 2.Patients with diabetes; 3.Patients with urine protein>3g/24h; 4.Patients with 18.5kg/m2>BMI>28 kg/m2; 5.Patients with the severity of edema higher than tree-degree; 6.Patients with serious liver dysfunction (ALT and AST above the normal upper limit by 2.5 times) and patients with cirrhosis; 7.Patients with serious cardiac dysfunction (NYHA grade III/IV); 8.Patients with Serious blood disease history (coagulation disorders or multiple myeloma); 9.Patients combined with malignant tumors; 10.Patients combined with Hyperthyroidism, hypothyroidism and Cushing's syndrome among other diseases which seriously influence nutrition metabolism; 11.Patient's urine volume <400ml/d before dialysis; 12.Patients with active bacterial or viral infection; 13.Patients already included in other clinical trials; 14.patients with an indication for enteral and parenteral nutrition; 15.Other patients who are considered not suitable to participate this study by investigators.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 24h urine test;Biochemical variables; | — |
Primary
| Measure | Time frame |
|---|---|
| Height;weight;Blood Pressure;Blood routine examination; | — |
Countries
China
Contacts
Peking Union Medical College Hospital