Chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: COPD group: 1) Chinese male or female outpatients aged 45 to 85 years; 2) Patients with a diagnosis of COPD, defined as 2013 GOLD guideline: Postbronchodilation FEV1/FVC ratio of <70%; 3) Patients who must be able to converse in and read. Patients who must also understand the study and give informed consent; Control group: 1) Over the same period, Patients without COPD; 2) Patients who must be able to converse in and read. Patients who must also understand the study and give informed consent.
Exclusion criteria
Exclusion criteria: 1. Cerebrovascular disease; 2. Intracranial infection and cerebral trauma; 3. Epilepsia; 4. Demyelinating disease of central nervous system; 5. Psychiatric disorders; 6. With severe disease such as heart failure, liver failure, kidney failure and tumour; 7. Patients with congenital mentally handicapped, illiteracy, and 8. Patients with concurrent respiratory disorders (e.g. asthma) other than COPD.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination( MMSE);amyloid-ß;Montreal Cognitive Assessment (MoCA);Fuld Object Memory Evaluation (FOM);Rapid Verbal Retrieve (RVR);imaging detection; | — |
Countries
China
Contacts
Department of Respiratory Medicine, Daping Hospital, The Third Military Medical University, Chongqing, China.