Skip to content

Predictive effect of CTC phenotype and CTGF gene expression in tumor recurrence and metastasis after liver transplantation for patients with hepatocellular carcinoma

Predictive effect of CTC phenotype and CTGF gene expression in tumor recurrence and metastasis after liver transplantation for patients with hepatocellular carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCN-15006949
Enrollment
Unknown
Registered
2015-08-21
Start date
2015-10-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

CTC High Group:Liver transplantation
CTC Low Group:Liver transplantation
CTGF High Group:Liver transplantation

Sponsors

General Hospital of Guangzhou Military Command of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 to 70 years old, male or female; 2. Pathological diagnosis of hepacellular carcinoma; 3. Other carcinoma and metastasis out of liver were excluded by preoperative PET/CT; 4. Add into wait-list and undergo liver transplantation surgery; 5. Regular follow-up after surgery; 6. Signed the informed consent.

Exclusion criteria

Exclusion criteria: Patient meet one of the following conditions will be excluded: (1) serious violation of the protocol (including poor compliance); (2) Multi-source tumor or extrahepatic metastases found preoperation; (3) Patient is not suitable to participate in research as evaluated by researchers.

Design outcomes

Primary

MeasureTime frame
CTC amount;Ratio of mesenchymal CTC;Expression Level of GTGF Gene;Progress free survival;Time to tumor progression;Objective tumor response rate;

Countries

China

Contacts

Public ContactWANG Shaoping
13600063713@163.com+86 13600063713

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026