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Association of polymorphism of TRPV1rs2277675 with fentanyl induced cough in Chinese patients

Association of polymorphism of TRPV1rs2277675 with fentanyl induced cough in Chinese patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCH-14005179
Enrollment
Unknown
Registered
2014-09-03
Start date
2014-09-03
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fentanyl induced cough

Interventions

fentanyl group:iv fentanyl

Sponsors

Department of Anesthesiology, The Third Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for various elective surgery under general anesthesia; 2. Age between 18-60 years; 3. Can give written consent by himself; 4. Adequate IV access; 5. ASA GRADE 1 and 2; 6. Patients of either sex.

Exclusion criteria

Exclusion criteria: 1. Patient having chronic obstructive airway disease, asthma, hypertension and any other systemic illness; 2. Upper respiratory tract infection within last 2 weeks; 3. Chronic smoker; 4. Patient on angiotensin converting enzyme inhibitor, bronchodilators and steroids; 5. Head and neck surgery; 6. Premedication; 7. Abnormal intracranial, intraocular and intraabdominal pressure; 8. History of allergy.

Design outcomes

Primary

MeasureTime frame
SNP;

Countries

China

Contacts

Public ContactDong Huang
huangdong6619@vip.163.com+86 13787412741

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026