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Comparison of corneal biomechanical characteristics between laser-assisted subepithelial keratectomy (LASEK) and small incision lenticule extraction (SMILE)

The research on the mechanism of complications after refractive surgery in use of corneal biomechanical and optical model

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCH-14005057
Enrollment
Unknown
Registered
2014-08-05
Start date
2011-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

refractive error

Interventions

laser-assisted subepithelial keratectomy group:laser-assisted subepithelial keratectomy
small incision lenticule extraction group:small incision lenticule extraction

Sponsors

Tianjin Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: normal corneal morphology with no corneal nebula or corneal macula; manifest spherical equivalent of -1 to -6 diopters (D), the cylindrical diopter less than -3.00D; refractive diopter maintained stable for more than 2 years; picked off soft contact lens for more than 2 weeks; picked off RGP for more than 1 month; preoperative corneal central thickness measured by Pentacam more than 500 um and non-contact IOP less than 21mmHg.

Exclusion criteria

Exclusion criteria: less than 18 years old; any corneal diseases, corneal operations, eyes trauma or systemic diseases history; keratoconus or susceptive keratoconus; especially corneal macula and obvious pannus.

Design outcomes

Primary

MeasureTime frame
cornea hysteresis;corneal resistance factor;—

Countries

China

Contacts

Public ContactYan Wang
wangyan7143@vip.sina.com+86 022 27305083

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026