Effects of gender on median effective target plasma concentration of propofol inhibiting responses to laryngeal mask airway insertion when combined with dexmedetomidine

Gender factor impacts dexmedetomidine plasma concentration of propofol inhibiting responses

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OCH-14004897

Enrollment

Unknown

Registered

2014-07-06

Start date

2014-07-20

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergoing elective surgeries

Interventions

Male:propofol+dexmedetomidine

Female:propofol+dexmedetomidine

Eligibility

Age

18 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective surgeries; 2.BMI 18.5~24.0 kg/m2 2. ASA physical status I or II; 3.Mallampati I or II; 4.Mouth opening greater than 2.5cm

Exclusion criteria

Exclusion criteria: 1.History of hypertension and gastroesophageal reflux; 2.Long history of taking sedatives or opioids; 3.Bradycardia or heart block; 4.Liver or kidney dysfunction.

Design outcomes

Primary

Measure	Time frame
whether responses to laryngeal mask airway inserti;	—

Countries

China

Contacts

Public ContactLi Juan

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026