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The expression of GASC1 and HIF-1a in esophageal squamous carcinoma and its relationship with chemotherapy curative effect and prognosis

The expression of GASC1 and HIF-1a in esophageal squamous carcinoma and its relationship with chemotherapy curative effect and prognosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCH-14004541
Enrollment
Unknown
Registered
2014-04-14
Start date
2009-12-12
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

high expression of GASC1:chemotherapy
lower expression of GASC1:chemotherapy
high expression of HIF-1a:chemotherapy
lower expression of HIF-1a:chemotherapy

Sponsors

1th Affiliated Hospital of Henan Univercity of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
43 Years to 75 Years

Inclusion criteria

Inclusion criteria: The pathological diagnosis, gastrointestinal barium meal and CT results diagnosed with advanced esophageal squamous cell carcinoma. All patients with new esophageal cancer didn,t accept any other treatment.

Exclusion criteria

Exclusion criteria: The patients with serious heart and head blood-vessel disease; The patients with serious Liver and kidney disease; The patients can not able to tolerate the chemotherapy.

Design outcomes

Primary

MeasureTime frame
Chemotherapy curative effect;—

Secondary

MeasureTime frame
4-years survival rate;—

Countries

China

Contacts

Public ContactShegan GAO

1st Affiliated Hospital of Henan Univercity of Science and Technology

gsg112258@163.com+86 18638859977

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 4, 2026