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Effects of Sodium Thiosulfate on Vascular Calcification in End-Stage Renal Disease

Effects of Sodium Thiosulfate on Vascular Calcification in End-Stage Renal Disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCH-14004133
Enrollment
Unknown
Registered
2014-01-05
Start date
2014-01-20
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vascular Calcification in End-Stage Renal Disease

Interventions

Test group:Sodium thiosulfate
Control group:Conventional therapy

Sponsors

Fuzhou General Hospital of Nanjing Military Command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. eGFR <15ml/min and hemodialysis patients; 2. patients with good adherence; 3. willingness to undergo intravenous sodium thiosulfate treatments for 5 months.

Exclusion criteria

Exclusion criteria: 1. aged <18 years; 2. life expectancy <6 months; 3. pregnancy; 4. current or recent (<12 months) treatment with corticosteroids; 5. current or recent (<12 months) treatment with Phosphate binders, active vitamin D and calcium; 6. Diabetes, hyperlipidemia, hypercalcemia.

Design outcomes

Primary

MeasureTime frame
Coronary artery calcification;Carotid intima-media thickness;—

Secondary

MeasureTime frame
PTH;Bone alkaline phosphatase;25-(OH)-D3;Phosphorus;Calcium;Liver functio;—

Countries

China

Contacts

Public ContactYU Yi

Fuzhou General Hospital of Nanjing Military Command, PLA

yuyicn@126.com+86 13600889152

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026