poor ovarian responers in women undergoing IVF/ICSI treatment
Conditions
Interventions
follicle-phase ovarian stimulation:mild stimulation
luteal-phase ovarian stimulation:letrozole and HMG
Sponsors
Shanghai Ninth People's Hospital
Eligibility
Sex/Gender
Female
Age
32 Years to 45 Years
Inclusion criteria
Inclusion criteria: patients had to meet at least two of the following criteria: 1. aged >40 years; 2. a history of ovarian surgery; 3. previous treatment using conventional protocols that yielded less than 3 oocytes; 4. antral follicle count of less than 5 on menstrual cycle day 2-3; 5. basal serum FSH concentration between 10 and 19 IU/l.
Exclusion criteria
Exclusion criteria: 1. clinically significant systemic disease such as renal failure; 2. documented ovarian failure; 3. endometriosis grade 3 or higher; 4. any contraindications to ovarian stimulation treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the number of oocyte retrieva; | — |
Secondary
| Measure | Time frame |
|---|---|
| the number of metaphase oocytes;the number of fertilized oocytes;the number of cleavaged embryos;the number of viable embryos;the clinical pregnancy rate in frozen-thawed embry;the implantation rate; | — |
Countries
China
Contacts
Public ContactYanping Kuang
Shanghai Ninth People's Hospital
Outcome results
None listed